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FXIIa-IN-2

FXIIa-IN-1-IN-2 (Compound 21) is a Factor XIIa inhibitor (Kiapp: 62.2 nM) . FXIIa-IN-1-IN-2 can be used for research of thrombosis[1].

Product Specifications

CAS Number

3052551-17-1

UNSPSC

12352005

Target

Thrombin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/fxiia-in-2.html

Solubility

10 mM in DMSO

Smiles

COC1=CC2=C(OC(C(C(OC3=CC4=CC=C(C(N)=N)C=C4C=C3)=O)=C2)=O)C=C1OC

Molecular Formula

C23H18N2O6

Molecular Weight

418.40

References & Citations

[1]Davoine C, et al. Coumarins as factor XIIa inhibitors: Potency and selectivity improvements using a fragment-based strategy. Eur J Med Chem. 2023 Jul 16;259:115636.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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