MmpL3-IN-3
MmpL3-IN-3 (Compound 12) is a MmpL3 inhibitor. MmpL3-IN-3 shows a MIC of 0.1 μM against H37Rv. MmpL3-IN-3 shows good stability in mouse liver microsomes. MmpL3-IN-3 can be used for anti-tubercular research[1].
Product Specifications
CAS Number
1639438-67-7
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mmpl3-in-3.html
Solubility
10 mM in DMSO
Smiles
CC1=C(CN2CC[Si](C)(C)CC2)C=C(C3=CC=C(Cl)C=C3)N1C4=CC=C(CC)C=C4
Molecular Formula
C26H33ClN2Si
Molecular Weight
437.09
References & Citations
[1]Vasudevan N, et al. Synthesis, biological evaluation and docking studies of silicon incorporated diarylpyrroles as MmpL3 inhibitors: An effective strategy towards development of potent anti-tubercular agents. Eur J Med Chem. 2023 Jul 16;259:115633.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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