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MmpL3-IN-3

MmpL3-IN-3 (Compound 12) is a MmpL3 inhibitor. MmpL3-IN-3 shows a MIC of 0.1 μM against H37Rv. MmpL3-IN-3 shows good stability in mouse liver microsomes. MmpL3-IN-3 can be used for anti-tubercular research[1].

Product Specifications

CAS Number

1639438-67-7

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mmpl3-in-3.html

Solubility

10 mM in DMSO

Smiles

CC1=C(CN2CC[Si](C)(C)CC2)C=C(C3=CC=C(Cl)C=C3)N1C4=CC=C(CC)C=C4

Molecular Formula

C26H33ClN2Si

Molecular Weight

437.09

References & Citations

[1]Vasudevan N, et al. Synthesis, biological evaluation and docking studies of silicon incorporated diarylpyrroles as MmpL3 inhibitors: An effective strategy towards development of potent anti-tubercular agents. Eur J Med Chem. 2023 Jul 16;259:115633.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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