Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Vem-L-Cy5

Vem-L-Cy5 (compound 3), modified with the NIR fluorophore cyanine-5 (Cy5), is a Vemurafenib (HY-12057) -based inhibitor of BRAF. Vem-L-Cy5 targets to BRAFV600E, and also inhibits MEK phosphorylation. Vem-L-Cy5 has cell permeability, and inhibits cell growth of many types of cancer[1].

Product Specifications

CAS Number

[3057544-65-4]

UNSPSC

12352005

Target

Raf

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/vem-l-cy5.html

Purity

98.31

Solubility

DMSO : 50 mg/mL

Smiles

CC1(C)C(/C=C/C=C/C=C2N(CCCCCC(NCCOCCOCC(NC3=CC=C(C4=CN=C(NC=C5C(C6=C(F)C=CC(NS(=O)(CCC)=O)=C6F)=O)C5=C4)C=C3)=O)=O)C7=C(C=CC=C7)C/2(C)C)=[N+](C)C8=C1C=CC=C8.O=C([O-])C(F)(F)F

Molecular Formula

C63H68F5N7O9S

Molecular Weight

1194.31

References & Citations

[1]Barresi E, et al. A cyanine-based NIR fluorescent Vemurafenib analog to probe BRAFV600E in cancer cells. Eur J Med Chem. 2023 Aug 5;256:115446.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NRIP2 Antibody

MBS8511004-01 0.05 mg

NRIP2 Antibody

Ask

NRIP2 Antibody

MBS8511004-02 0.1 mg

NRIP2 Antibody

Ask

NRIP2 Antibody

MBS8511004-03 0.1 mL (AF750)

NRIP2 Antibody

Ask

NRIP2 Antibody

MBS8511004-04 0.1 mL (AF405M)

NRIP2 Antibody

Ask

NRIP2 Antibody

MBS8511004-05 0.1 mL (AF546)

NRIP2 Antibody

Ask

NRIP2 Antibody

MBS8511004-06 0.1 mL (AF405L)

NRIP2 Antibody

Ask