Tubulin inhibitor 37
Tubulin inhibitor 37 (Compound 12) is a Tubulin inhibitor that can effectively inhibit Tubulin aggregation (IC50=1.3 µM) . Tubulin inhibitor 37 exhibits antiproliferative activity against human tumor cell lines and has potential for studying cancer[1].
Product Specifications
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-inhibitor-37.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC(C2=NN=NN2C3=CC=C(N(C)C=C4C=O)C4=C3)=CC(Cl)=N1
Molecular Formula
C16H10Cl2N6O
Molecular Weight
373.20
References & Citations
[1]Gallego-Yerga L, et al. Novel Tetrazole Derivatives Targeting Tubulin Endowed with Antiproliferative Activity against Glioblastoma Cells. Int J Mol Sci. 2023 Jul 4;24 (13) :11093.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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