Tubulin inhibitor 37

Tubulin inhibitor 37 (Compound 12) is a Tubulin inhibitor that can effectively inhibit Tubulin aggregation (IC50=1.3 µM) . Tubulin inhibitor 37 exhibits antiproliferative activity against human tumor cell lines and has potential for studying cancer[1].

Product Specifications

UNSPSC

12352005

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tubulin-inhibitor-37.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC(C2=NN=NN2C3=CC=C(N(C)C=C4C=O)C4=C3)=CC(Cl)=N1

Molecular Formula

C16H10Cl2N6O

Molecular Weight

373.20

References & Citations

[1]Gallego-Yerga L, et al. Novel Tetrazole Derivatives Targeting Tubulin Endowed with Antiproliferative Activity against Glioblastoma Cells. Int J Mol Sci. 2023 Jul 4;24 (13) :11093.