Garcinone B
Garcinone B, a xanthone derivative, is a nature product that could be isolated from the pericarp of Mangosteen. Garcinone B is a potent ACE2 and Mpro inhibitor. Garcinone B can be used in research of COVID-19[1].
Product Specifications
CAS Number
[76996-28-6]
UNSPSC
12352005
Target
Angiotensin-converting Enzyme (ACE) ; SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/garcinone-b.html
Solubility
10 mM in DMSO
Smiles
OC(C(C/C=C(C)/C)=C1O)=CC2=C1C(C3=C4C(OC(C)(C)C=C4)=C(O)C=C3O2)=O
Molecular Formula
C23H22O6
Molecular Weight
394.42
References & Citations
[1]Suhandi C, et, al. for COVID-19 Treatment through Angiotensin-Converting Enzyme 2 and Main Protease Blockade: A Computational Study. Molecules. 2023 Jul 4;28 (13) :5187.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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