Garcinone B

Garcinone B, a xanthone derivative, is a nature product that could be isolated from the pericarp of Mangosteen. Garcinone B is a potent ACE2 and Mpro inhibitor. Garcinone B can be used in research of COVID-19[1].

Product Specifications

CAS Number

[76996-28-6]

UNSPSC

12352005

Target

Angiotensin-converting Enzyme (ACE) ; SARS-CoV

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/garcinone-b.html

Solubility

10 mM in DMSO

Smiles

OC(C(C/C=C(C)/C)=C1O)=CC2=C1C(C3=C4C(OC(C)(C)C=C4)=C(O)C=C3O2)=O

Molecular Formula

C23H22O6

Molecular Weight

394.42

References & Citations

[1]Suhandi C, et, al. for COVID-19 Treatment through Angiotensin-Converting Enzyme 2 and Main Protease Blockade: A Computational Study. Molecules. 2023 Jul 4;28 (13) :5187.