HDAC6-IN-16
Product Specifications
UNSPSC Description
HDAC6-IN-16 (compound 5c) is a histone deacetylase 6 (HDAC6) inhibitor, based on Quinazolin-4(3H)-One. HDAC6-IN-16 exhibits anticancer effect, inhibits colony-forming. And HDAC6-IN-16 arrests cell cycle at G2 phase and induces apoptosis[1].
Target Antigen
Apoptosis; HDAC
Type
Reference compound
Related Pathways
Apoptosis;Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac6-in-16.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=CC=C(C)C=C2)C(SCC3=CC=C(C(NO)=O)C=C3)=NC4=CC=CC=C41
Molecular Weight
417.48
References & Citations
[1]Khetmalis YM, et al. Design, Synthesis, and Biological Evaluation of Novel Quinazolin-4(3H)-One-Based Histone Deacetylase 6 (HDAC6) Inhibitors for Anticancer Activity. Int J Mol Sci. 2023 Jul 3;24(13):11044.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149371/HDAC6-IN-16-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149371/
Clinical Information
No Development Reported
Curated Selection
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