Yhhu6669
Yhhu6669 is an anti-HBV agent. Yhhu6669 inhibits HBV DNA. Yhhu6669 inhibits HBV replication by inducing the formation of DNA-free capsids. Yhhu6669 decreases HBV DNA and HBcAg in AAV/HBV-infected mice. Yhhu6669 has favorable PK properties[1].
Product Specifications
CAS Number
2569526-80-1
UNSPSC
12352005
Target
HBV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/yhhu6669.html
Solubility
10 mM in DMSO
Smiles
ClC1=C(NCCCOC([C@@H](N)C(C)C)=O)N=C(F)C(C(C2=C3C=CC=C2)=NN(CC4=CC=C(C#N)C=C4)C3=O)=C1
Molecular Formula
C29H28ClFN6O3
Molecular Weight
563.02
References & Citations
[1]Chen W, et al. A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B. Eur J Med Chem. 2023 Sep 5;257:115485.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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