Antibacterial agent 145
Antibacterial agent 145 (compound 1b) is an antibacterial agent depending on bacterial iron uptake pathway. Antibacterial agent 145 disrupts cytoplasmic membrane integrity and inhibits cell metabolism but exhibits low cytotoxic effects to normal cells[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-145.html
Solubility
10 mM in DMSO
Smiles
C/C(C)=C/CC1=C(O)C=CC(C(/C=C/C2=CC=C(OCCCOCC(N(C)C=C3O)=CC3=O)C=C2)=O)=C1O
Molecular Formula
C30H33NO7
Molecular Weight
519.59
References & Citations
[1]Huang YJ, et al. 3-Hydroxy-pyridin-4 (1H) -ones as siderophores mediated delivery of isobavachalcone enhances antibacterial activity against pathogenic Pseudomonas aeruginosa. Eur J Med Chem. 2023 Sep 5;257:115454.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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