MtUng-IN-1
MtUng-IN-1 (Compound 18a) is a Uracil DNA glycosylase of Mycobacterium (MtUng) inhibitor (IC50: 300 μM) . MtUng-IN-1 can be used for research of cancers and infectious diseases[1].
Product Specifications
CAS Number
[359826-99-6]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/mtung-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(NC/1=O)=O)C1=C/C2=CC=C(OCC(OC)=O)C=C2
Molecular Formula
C14H12N2O6
Molecular Weight
304.25
References & Citations
[1]Kesharwani S, et al. Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur J Med Chem. 2023 Oct 5;258:115604.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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