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IRAK4-IN-24

IRAK4-IN-24 (compound 16) is a potent IRAK4 inhibitor, with high clearance (Cl) and poor oral bioavailability. IRAK4-IN-24 can be used for research in inflammatory and autoimmune disorders.

Product Specifications

CAS Number

2952533-54-7

UNSPSC

12352005

Target

IRAK

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/irak4-in-24.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC=CC(C2=CN(C)N=C2)=N1)C3=CC(CC(C)(C)O4)=C4N=C3O

Molecular Formula

C19H19N5O3

Molecular Weight

365.39

References & Citations

[1]Hao Y, et al. Synthesis and evaluation of dihydrofuro [2, 3-b] pyridine derivatives as potent IRAK4 inhibitors[J]. European Journal of Medicinal Chemistry, 2023: 115616.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

IRAK4

Frequently Asked Questions

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