IRAK4-IN-24
IRAK4-IN-24 (compound 16) is a potent IRAK4 inhibitor, with high clearance (Cl) and poor oral bioavailability. IRAK4-IN-24 can be used for research in inflammatory and autoimmune disorders.
Product Specifications
CAS Number
2952533-54-7
UNSPSC
12352005
Target
IRAK
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/irak4-in-24.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=CC(C2=CN(C)N=C2)=N1)C3=CC(CC(C)(C)O4)=C4N=C3O
Molecular Formula
C19H19N5O3
Molecular Weight
365.39
References & Citations
[1]Hao Y, et al. Synthesis and evaluation of dihydrofuro [2, 3-b] pyridine derivatives as potent IRAK4 inhibitors[J]. European Journal of Medicinal Chemistry, 2023: 115616.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IRAK4
Frequently Asked Questions
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