α-Glucosidase-IN-28
α-Glucosidase-IN-28 (Compound 18) is a α-Glucosidase inhibitor (IC50: 0.62 μM, Ki: 3.93 μM) . α-Glucosidase-IN-28 binds to α-glucosidase at the original binding site (OBS), and forms multiple hydrophobic interactions with nearby amino acids. α-Glucosidase-IN-28 can be used for research of diabetes and related diseases[1].
Product Specifications
CAS Number
2949513-10-2
UNSPSC
12352005
Target
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-glucosidase-in-28.html
Solubility
10 mM in DMSO
Smiles
OC(C1=CC=CC=C1O2)=C(C(C3=CC(Br)=C(OCCCC)C(Br)=C3)C4=C(O)C(C=CC=C5)=C5OC4=O)C2=O
Molecular Formula
C29H22Br2O7
Molecular Weight
642.29
References & Citations
[1]Phan TH, et al. Designing Potent -Glucosidase Inhibitors: A Synthesis and QSAR Modeling Approach for Biscoumarin Derivatives. ACS Omega. 2023 Jul 11;8 (29) :26340-26350.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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