D1R antagonist 1
D1R antagonist 1 (compound 12a) is a D1R antagonist, involved in G-protein- and β-arrestin-based signaling[1].
Product Specifications
CAS Number
2983777-67-7
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d1r-antagonist-1.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C=C(C2=C1)CCN3[C@H]2CC4=C(C=C(C(OCC)=C4C3)O)Br)OCCC
Molecular Formula
C22H26BrNO4
Molecular Weight
448.35
References & Citations
[1]Namballa HK, et al. Discovery of Selective Dopamine Receptor Ligands Derived from (-) -Stepholidine via C-3 Alkoxylation and C-3/C-9 Dialkoxylation. J Med Chem. 2023 Jul 27;66 (14) :10060-10079.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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