BO-1
BO-1 is a benzoate ester with antibacterial activity. BO-1 inhibits multidrug-resistant Staphylococcus aureus, and acts function synergistically with antibiotic, such as Ciprofloxacin. BO-1 can reverse the resistance of antibiotic-resistant S. aureus strains, and decreases the level of inflammatory factors IL-6 and C-reactive protein in vivo in mice[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bo-1.html
Solubility
10 mM in DMSO
Smiles
O[C@]1(COC(C2=CC=CC=C2)=O)[C@H](Cl)C=C[C@@H](OC(C3=CC=CC=C3)=O)[C@@H]1O
Molecular Formula
C21H19ClO6
Molecular Weight
402.82
References & Citations
[1]Xiao CY, et al. Natural Product BO-1 as an Inner Responsive Molecule Inhibits Antimicrobial-Resistant Staphylococcus aureus via Synergism. ACS Infect Dis. 2023 Aug 11;9 (8) :1523-1533.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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