α-Glucosidase-IN-26
α-Glucosidase-IN-26 (Compound 7i) is an α-glucosidase inhibitor (IC50=4.63 µM) . α-Glucosidase-IN-26 can be used in the study of type 2 diabetes mellitus (T2DM) [1].
Product Specifications
UNSPSC
12352005
Target
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-glucosidase-in-26.html
Solubility
10 mM in DMSO
Smiles
O=C(C1(CC2=CN(C3=CC=C(Cl)C=C3)N=N2)CC4=CC=C(OC)C=C4)OC(C)(C)OC1=O
Molecular Formula
C23H22ClN3O5
Molecular Weight
455.89
References & Citations
[1]Avula SK, et al. Meldrum-Based-1H-1,2,3-Triazoles as Antidiabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition Activity, Molecular Docking Studies, and In Silico Approach. ACS Omega. 2023 Jul 7;8 (28) :24901-24911.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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