SDH-IN-4
SDH-IN-4 (compound B6) is a selective inhibitor against succinate dehydrogenase (SDH) with an IC50 value of 0.28 μg/mL. SDH-IN-4 has highly efficient and broad-spectrum antifungal activity, against R. solani with an EC50 value of 0.23 μg/mL[1].
Product Specifications
CAS Number
2982993-88-2
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sdh-in-4.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=C(C)NN=C1C(F)(F)F)(NNC2=CC=C(Cl)C=C2Cl)=O
Molecular Formula
C11H9Cl2F3N4O2S
Molecular Weight
389.18
References & Citations
[1] Chai JQ, et al. Potential Succinate Dehydrogenase Inhibitors Bearing a Novel Pyrazole-4-sulfonohydrazide Scaffold: Molecular Design, Antifungal Evaluation, and Action Mechanism. J Agric Food Chem. 2023 Jun 21;71 (24) :9266-9279.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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