SDH-IN-4
SDH-IN-4 (compound B6) is a selective inhibitor against succinate dehydrogenase (SDH) with an IC50 value of 0.28 μg/mL. SDH-IN-4 has highly efficient and broad-spectrum antifungal activity, against R. solani with an EC50 value of 0.23 μg/mL[1].
Product Specifications
CAS Number
2982993-88-2
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sdh-in-4.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=C(C)NN=C1C(F)(F)F)(NNC2=CC=C(Cl)C=C2Cl)=O
Molecular Formula
C11H9Cl2F3N4O2S
Molecular Weight
389.18
References & Citations
[1] Chai JQ, et al. Potential Succinate Dehydrogenase Inhibitors Bearing a Novel Pyrazole-4-sulfonohydrazide Scaffold: Molecular Design, Antifungal Evaluation, and Action Mechanism. J Agric Food Chem. 2023 Jun 21;71 (24) :9266-9279.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
17259121 3x 1.0µg DNA
CYCSP19 CRISPRa sgRNA lentivector (set of three targets)(Human)
Sign In for Pricing
View Details bs-4266R-BF750 100 µL
Cip4 Polyclonal Antibody, AbBy Fluor™ 750 Conjugated
Sign In for Pricing
View Details