Acryl42-10
Acryl42-10 is a covalent inhibitor of the SARS-CoV-2 Nsp14 N7-Methyltransferase (IC50: 7 μM) [1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/acryl42-10.html
Solubility
10 mM in DMSO
Smiles
C=CC(NCC(OC)C(N1CCC(C2C(NC3=C2C=CC(Cl)=C3)=O)CC1)=O)=O
Molecular Formula
C20H24ClN3O4
Molecular Weight
405.88
References & Citations
[1]Singh I, et al. Structure-Based Discovery of Inhibitors of the SARS-CoV-2 Nsp14 N7-Methyltransferase. J Med Chem. 2023 Jun 22;66 (12) :7785-7803.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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