CYCA-117-70
CYCA-117-70 is a DCAF1 ligand (KD: 70 μM) . CYCA-117-70 is an ideal chemical handles for PROTACs recruiting DCAF1[1].
Product Specifications
CAS Number
1958262-04-8
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cyca-117-70.html
Solubility
10 mM in DMSO
Smiles
FC1=CC(N(C2)CCCC2NC3=NC=NC(N4CCOCC4)=C3)=CC=C1
Molecular Formula
C19H24FN5O
Molecular Weight
357.43
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]Kimani SW, et al. Discovery of a Novel DCAF1 Ligand Using a Drug-Target Interaction Prediction Model: Generalizing Machine Learning to New Drug Targets. J Chem Inf Model. 2023 Jul 10;63 (13) :4070-4078.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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