CYCA-117-70
CYCA-117-70 is a DCAF1 ligand (KD: 70 μM) . CYCA-117-70 is an ideal chemical handles for PROTACs recruiting DCAF1[1].
Product Specifications
CAS Number
1958262-04-8
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cyca-117-70.html
Solubility
10 mM in DMSO
Smiles
FC1=CC(N(C2)CCCC2NC3=NC=NC(N4CCOCC4)=C3)=CC=C1
Molecular Formula
C19H24FN5O
Molecular Weight
357.43
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]Kimani SW, et al. Discovery of a Novel DCAF1 Ligand Using a Drug-Target Interaction Prediction Model: Generalizing Machine Learning to New Drug Targets. J Chem Inf Model. 2023 Jul 10;63 (13) :4070-4078.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC421751 20 µg
CCDC56 (COA3) (NM_001040431) Human Over-expression Lysate
Sign In for Pricing
View Details 
BNC942242-500 1x 500 µL
Glutathione S-Transferase Mu2 (GSTM2) (CPTC-GSTMu2-2), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 