PptT-IN-4
PptT-IN-4 (Compound 3a) is a PptT inhibitor (IC50: 0.71 μM) . PptT-IN-4 inhibits Mtb H37Rv with a MIC value of 42 μM. PptT-IN-4 also inhibits hERG, hCav1.2, and hNav1.5 channels with IC50s of 11 μM, 8.1 μM, 6.9 μM respectively[1].
Product Specifications
CAS Number
2948309-57-5
UNSPSC
12352005
Target
Bacterial; Calcium Channel; Potassium Channel; Sodium Channel
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pptt-in-4.html
Solubility
10 mM in DMSO
Smiles
CCC1=C(NC2=CC=CC(NCC)=N2)C(CC)=CC=C1
Molecular Formula
C17H23N3
Molecular Weight
269.38
References & Citations
[1]Ottavi S, et al. Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas. ACS Med Chem Lett. 2023 Jun 26;14 (7) :970-976.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS2054068-01 0.1 mL
PE-Linked Polyclonal Antibody to Elastin (ELN)
Sign In for Pricing
View Details MBS2054068-02 0.2 mL
PE-Linked Polyclonal Antibody to Elastin (ELN)
Sign In for Pricing
View Details MBS2054068-03 0.5 mL
PE-Linked Polyclonal Antibody to Elastin (ELN)
Sign In for Pricing
View Details MBS2054068-06 5x 5 mL
PE-Linked Polyclonal Antibody to Elastin (ELN)
Sign In for Pricing
View Details