PSMA-IN-2
Product Specifications
UNSPSC Description
PSMA-IN-2 is an inhibitor of PSMA with a Ki value of 1.07 nM. PSMA-IN-2 displays favorable in vivo NIR imaging (λEM = 1088 nm, λex = 808 nm), and can be used for NIRII image-guided tumor resection surgery in PSMA-positive tumor-bearing mice[1].
Target Antigen
PSMA
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/psma-in-2.html
Solubility
10 mM in DMSO
Smiles
CN(C1=CC=C(C2=C3N=S=NC3=C(C4=NSN=C42)C5=CC=C(C=C5)N(C)CCC(NCCCC[C@H](NC(N[C@H](C(O)=O)CNC(C6=O)=C(C6=O)O)=O)C(O)=O)=O)C=C1)CCC(NCCCC[C@H](NC(N[C@H](C(O)=O)CNC(C7=O)=C(C7=O)O)=O)C(O)=O)=O
Molecular Weight
1257.27
References & Citations
[1]Wang X, et al. Design and Characterization of Squaramic Acid-Based Prostate-Specific Membrane Antigen Inhibitors for Prostate Cancer. J Med Chem. 2023 May 25;66(10):6889-6904.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149298/PSMA-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149298/
Clinical Information
No Development Reported
CAS Number
2946600-14-0
Curated Selection
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