DNMT-IN-3
DNMT-IN-3 is an DNA Methyltransferase (DNMT) inhibitor, and plays an antimalarial role with IC50 of 60 nM against Plasmodium falciparum (Plasmodium) . DNMT-IN-3 can be used for malaria related research[1].
Product Specifications
CAS Number
1683516-27-9
UNSPSC
12352005
Target
DNA Methyltransferase; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dnmt-in-3.html
Solubility
10 mM in DMSO
Smiles
C1(NCCNC2=CC=CC3=C2C=CC=C3)=C4C=CC(OCC5CCN(CC5)CCNC6=C7C=CC=CC7=NC=C6)=CC4=NC=N1
Molecular Formula
C37H39N7O
Molecular Weight
597.75
References & Citations
[1]Dobrescu I, et.al. Plasmodium falciparum Eukaryotic Translation Initiation Factor 3 is Stabilized by Quinazoline-Quinoline Bisubstrate Inhibitors. ACS Infect Dis. 2023 Jun 9; 9 (6) :1257-1266.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
