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PLpro/RBD-IN-1

PLpro/RBD-IN-1 (compound 5) is a dual SARS-CoV-2 PLpro and spike protein RBD inhibitor with IC50s of 7.197 μM and 8.673 μM, respectively[1].

Product Specifications

CAS Number

1282451-83-5

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/plpro-rbd-in-1.html

Solubility

10 mM in DMSO

Smiles

NC1=C(C=CC=C1)C2=NOC(C3=CC=NC=C3)=N2

Molecular Formula

C13H10N4O

Molecular Weight

238.24

Precautions

P261-P280-P302+P352

References & Citations

[1]Mohammed Salah Ayoup, et al. Repurposing 1,2,4-oxadiazoles as SARS-CoV-2 PLpro inhibitors and investigation of their possible viral entry blockade potential. Eur J Med Chem. 2023 Apr 5;252:115272.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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