PLpro/RBD-IN-1
PLpro/RBD-IN-1 (compound 5) is a dual SARS-CoV-2 PLpro and spike protein RBD inhibitor with IC50s of 7.197 μM and 8.673 μM, respectively[1].
Product Specifications
CAS Number
[1282451-83-5]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/plpro-rbd-in-1.html
Solubility
10 mM in DMSO
Smiles
NC1=C(C=CC=C1)C2=NOC(C3=CC=NC=C3)=N2
Molecular Formula
C13H10N4O
Molecular Weight
238.24
Precautions
P261-P280-P302+P352
References & Citations
[1]Mohammed Salah Ayoup, et al. Repurposing 1,2,4-oxadiazoles as SARS-CoV-2 PLpro inhibitors and investigation of their possible viral entry blockade potential. Eur J Med Chem. 2023 Apr 5;252:115272.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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