DENV-IN-10
DENV-IN-10 is a potent tetravalent dengue inhibitor, with EC50s of 1.36, 0.87, 0.94, and 0.95 μM against DENV-1-4 serotypes, respectively. DENV-IN-10 is a post-entry replication inhibitor that appears to be specific for cells of primate origin[1].
Product Specifications
UNSPSC
12352005
Target
Dengue Virus; Flavivirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/denv-in-10.html
Solubility
10 mM in DMSO
Smiles
CCCOC1=CC=C(C(C(NCC2=CC=CC=C2)=O)=C1)NS(=O)(C3=CC=CC4=C3N=CC=C4)=O
Molecular Formula
C26H25N3O4S
Molecular Weight
475.56
References & Citations
[1]Felicetti T, et, al. Functionalized sulfonyl anthranilic acid derivatives inhibit replication of all the four dengue serotypes. Eur J Med Chem. 2023 Apr 5;252:115283.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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