Anticancer agent 108
Anticancer agent 108 (Compound 3.10) is a potent P-gp inhibitor with significant antitumor activity and less toxicity to normal and pseudonormal cells. Anticancer agent 108 (Compound 3.10) had no acute toxic effect on С57BL/6 mice[1].
Product Specifications
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-108.html
Solubility
10 mM in DMSO
Smiles
O=C1NC2=C(C(C3=C(C(C4=C(C(O)=CC=C4)C3=O)=O)S2)C5=CC=CO5)S1
Molecular Formula
C18H9NO5S2
Molecular Weight
383.40
References & Citations
[1]Ivasechko I, et al. Molecular design, synthesis and anticancer activity of new thiopyrano[2,3-d]thiazoles based on 5-hydroxy-1,4-naphthoquinone (juglone) . Eur J Med Chem. 2023 Apr 5;252:115304.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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