Topo II/HDAC-IN-2
Product Specifications
UNSPSC Description
Topo II/HDAC-IN-2 (8d) exhibits excellent dual inhibitory activities against Topo II and HDAC. Topo II/HDAC-IN-2 (8d) induces apoptosis[1].
Target Antigen
Apoptosis; HDAC; Topoisomerase
Type
Reference compound
Related Pathways
Apoptosis;Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topo-ii-hdac-in-2.html
Solubility
10 mM in DMSO
Smiles
CCN1C(C2=C(C3=C(N2)C=CC=C3)N=C1SCCCCC(NO)=O)=O
Molecular Weight
360.43
References & Citations
[1]Mengmiao Zhao,
et al. Design, synthesis and biological evaluation of dual Topo II/HDAC
inhibitors bearing pyrimido[5,4-b]indole and pyrazolo[3,4-d]pyrimidine motifs. Eur
J Med Chem. 2023 Apr 5;252:115303.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149239/Topo-II-HDAC-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149239/
Clinical Information
No Development Reported
CAS Number
2922269-24-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal Stargazin Antibody (S245-36) [Alexa Fluor 647]](https://cdn.genprice.uk/genprice/genprice2.png)
NBP2-22411AF647 0.1 mL
Mouse Monoclonal Stargazin Antibody (S245-36) [Alexa Fluor 647]
Ask
View Details 