BIBD-124

BIBD-124 binds amyloid beta (Aβ) plaque with an IC50 value of 9.51 nM. [18F]BIBD-124 can be used as radiotracer of Aβ plaques[1].

Product Specifications

CAS Number

2716871-93-9

UNSPSC

12352005

Target

Amyloid-β

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bibd-124.html

Solubility

10 mM in DMSO

Smiles

CNC1=CC=C(C=N1)/C=C/C2=CN=C(C=C2)OCCOCCOCCF

Molecular Formula

C19H24FN3O3

Molecular Weight

361.41

References & Citations

[1]Zheng W, et al. Synthesis and In Vitro and In Vivo Evaluation of 18F-Labeled Positron Emission Tomography Tracers for Imaging Aβ Plaques. ACS Chem Neurosci. 2023 Mar 1;14 (5) :988-1003.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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