BIBD-124
BIBD-124 binds amyloid beta (Aβ) plaque with an IC50 value of 9.51 nM. [18F]BIBD-124 can be used as radiotracer of Aβ plaques[1].
Product Specifications
CAS Number
2716871-93-9
UNSPSC
12352005
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bibd-124.html
Solubility
10 mM in DMSO
Smiles
CNC1=CC=C(C=N1)/C=C/C2=CN=C(C=C2)OCCOCCOCCF
Molecular Formula
C19H24FN3O3
Molecular Weight
361.41
References & Citations
[1]Zheng W, et al. Synthesis and In Vitro and In Vivo Evaluation of 18F-Labeled Positron Emission Tomography Tracers for Imaging Aβ Plaques. ACS Chem Neurosci. 2023 Mar 1;14 (5) :988-1003.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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