CXJ-2
Product Specifications
UNSPSC Description
CXJ-2 is a cyclic peptide, and exhibits moderate affinity toward elastin derived peptides (EDPs). CXJ-2 exhibits potent activities to inhibit the PI3K/ERK pathway and decrease hepatic stellate cell proliferation and migration. CXJ-2 possesses potent antifibrotic efficacy[1].
Target Antigen
ERK; PI3K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway;PI3K/Akt/mTOR;Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cxj-2.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC1=O)C(C)C)N[C@](CC)(C(NCC(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N3[C@H](C(N[C@H]1C)=O)CCC3)=O)CO)=O)C)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC(N)=O)=O)C)=O)CO)=O)CCC2)=O)CO)=O)=O)C
Molecular Weight
1310.37
References & Citations
[1]Song N, et al. Design and Discovery of Novel Cyclic Peptides as EDPs-EBP Interaction Inhibitors for the Treatment of Liver Fibrosis. J Med Chem. 2023 Apr 13;66(7):4689-4702.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149205/CXJ-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149205/
Clinical Information
No Development Reported
CAS Number
2919976-92-2
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