5′-Amino-5′-deoxythymidine
5′-Amino-5′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-amino-5-deoxythymidine.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@@H](CN)O[C@@H](N2C(NC(C(C)=C2)=O)=O)C1
Molecular Formula
C10H15N3O4
Molecular Weight
241.24
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149160/5-Amino-5-deoxythymidine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149160/
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
CAS Number
[25152-20-9]
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