ITH12711
ITH12711 is a PP2A ligand. ITH12711 is able to cross the blood-brain barrier (BBB) . ITH12711 exerts neuroprotection via restoration of PP2A-phosphatase activity[1].
Product Specifications
CAS Number
3042876-07-0
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ith12711.html
Solubility
10 mM in DMSO
Smiles
CC1(O[C@]2([H])[C@](CO1)([H])O[C@@H](C=C2)C[C@H](O)CO)C
Molecular Formula
C12H20O5
Molecular Weight
244.28
References & Citations
[1]Raquel L Arribas, et al. C-glycosides analogues of the okadaic acid central fragment exert neuroprotection via restoration of PP2A-phosphatase activity: A rational design of potential drugs for Alzheimer's disease targeting tauopathies. Eur J Med Chem. 2023 May 5;251:115245.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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