Neuraminidase-IN-16

Neuraminidase-IN-16 (Compound 43b) is a potent neuraminidase inhibitor with IC50s of 0.031, 0.15, 0.25, 0.60, 0.63 and 10.08 μM against neuraminidase of H5N1, H5N8, H1N1, H3N2, H5N1-H274Y and H1N1-H274Y, respectively[1].

Product Specifications

UNSPSC

12352005

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/neuraminidase-in-16.html

Solubility

10 mM in DMSO

Smiles

CCC(O[C@@H]1C=C(C[C@@H]([C@H]1NC(C)=O)NCC2=CC=C(C(F)=C2)C3=CCCC3)C(O)=O)CC

Molecular Formula

C26H35FN2O4

Molecular Weight

458.57

References & Citations

[1]Jia R, et al. Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like properties. Eur J Med Chem. 2023 Apr 5;252:115275.