Neuraminidase-IN-16
Product Specifications
UNSPSC Description
Neuraminidase-IN-16 (Compound 43b) is a potent neuraminidase inhibitor with IC50s of 0.031, 0.15, 0.25, 0.60, 0.63 and 10.08 μM against neuraminidase of H5N1, H5N8, H1N1, H3N2, H5N1-H274Y and H1N1-H274Y, respectively[1].
Target Antigen
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/neuraminidase-in-16.html
Solubility
10 mM in DMSO
Smiles
CCC(O[C@@H]1C=C(C[C@@H]([C@H]1NC(C)=O)NCC2=CC=C(C(F)=C2)C3=CCCC3)C(O)=O)CC
Molecular Weight
458.57
References & Citations
[1]Jia R, et al. Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like properties. Eur J Med Chem. 2023 Apr 5;252:115275.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149088/Neuraminidase-IN-16-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149088/
Clinical Information
No Development Reported
Curated Selection
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