LTB4 antagonist 2
LTB4 antagonist 2, a carboxamide-acid compound, is an antagonist of leukotriene B4 (LTB4) with potentially anti-inflammatory activity. LTB4 antagonist 2 shows good affinity for the LTB4 receptor with IC50 of 439 nM[1].
Product Specifications
CAS Number
2929239-85-8
UNSPSC
12352005
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ltb4-antagonist-2.html
Solubility
10 mM in DMSO
Smiles
CN(C(C1=C(OC2=CC=C(C=C2O1)OCC3=CC=CC=C3)C(O)=O)=O)CCC4=CC=CC=C4
Molecular Formula
C26H23NO6
Molecular Weight
445.46
References & Citations
[1]Bouissane L, et al. New and promising type of leukotriene B4 (LTB4) antagonists based on the 1,4-benzodioxine structure. Eur J Med Chem. 2023 Jun 5;254:115332.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LTB4
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