LTB4 antagonist 1
LTB4 antagonist 1, a carboxamide-acid compound, is a potent Leukotriene B4 (LTB4) antagonist with an IC50 of 288 nM. LTB4 antagonist 1 has significant anti-inflammatory properties[1].
Product Specifications
CAS Number
2929239-84-7
UNSPSC
12352005
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ltb4-antagonist-1.html
Solubility
10 mM in DMSO
Smiles
CN(C(C1=C(OC2=CC(OCC3=CC=CC=C3)=CC=C2O1)C(O)=O)=O)CCC4=CC=CC=C4
Molecular Formula
C26H23NO6
Molecular Weight
445.46
References & Citations
[1]Latifa Bouissane, et al. New and promising type of leukotriene B4 (LTB4) antagonists based on the 1,4-benzodioxine structure. Eur J Med Chem. 2023 Apr 6;254:115332.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LTB4
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