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LTB4 antagonist 1

LTB4 antagonist 1, a carboxamide-acid compound, is a potent Leukotriene B4 (LTB4) antagonist with an IC50 of 288 nM. LTB4 antagonist 1 has significant anti-inflammatory properties[1].

Product Specifications

CAS Number

2929239-84-7

UNSPSC

12352005

Target

Leukotriene Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ltb4-antagonist-1.html

Solubility

10 mM in DMSO

Smiles

CN(C(C1=C(OC2=CC(OCC3=CC=CC=C3)=CC=C2O1)C(O)=O)=O)CCC4=CC=CC=C4

Molecular Formula

C26H23NO6

Molecular Weight

445.46

References & Citations

[1]Latifa Bouissane, et al. New and promising type of leukotriene B4 (LTB4) antagonists based on the 1,4-benzodioxine structure. Eur J Med Chem. 2023 Apr 6;254:115332.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

LTB4

Frequently Asked Questions

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