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HGAPDH-IN-1

HGAPDH-IN-1, a 3-bromo-4,5-dihydroisoxazole derivative, is a specific and potent hGAPDH covalent inhibitor. hGAPDH-IN-1 reduces cancer cell growth in different pancreatic cancer cell lines.

Product Specifications

UNSPSC

12352005

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hgapdh-in-1.html

Solubility

10 mM in DMSO

Smiles

BrC1=NOC2(C1)CCCC3=C2C=CC=C3

Molecular Formula

C12H12BrNO

Molecular Weight

266.13

References & Citations

[1]Andrea Galbiati, et al. Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells. Eur J Med Chem. 2023 Apr 6;254:115286.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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