3′-Azido-2′,3′-dideoxy-5-hydroxyuridine
3′-Azido-2′,3′-dideoxy-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[111495-90-0]
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-azido-2-3-dideoxy-5-hydroxyuridine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](N=[N+]=[N-])C[C@H](N(C(N2)=O)C=C(O)C2=O)O1
Molecular Formula
C9H11N5O5
Molecular Weight
269.21
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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