TSC25
Product Specifications
UNSPSC Description
TSC25 is a potent cruzipain (CZP) inhibitor, with an IC50 of 3.34 nM and a pIC50 of 8.48[1].
Target Antigen
Cathepsin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tsc25.html
Solubility
10 mM in DMSO
Smiles
NC(N/N=C(C1=CC=C(C(Cl)=C1)Cl)\CCN2CCOCC2)=S
Molecular Weight
361.29
References & Citations
[1]Jasinski G, et al. Design, synthesis and biological evaluation of novel thiosemicarbazones as cruzipain inhibitors. Eur J Med Chem. 2023 Apr 7;254:115345.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149069/TSC25-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149069/
Clinical Information
No Development Reported
Curated Selection
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