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TSC25

TSC25 is a potent cruzipain (CZP) inhibitor, with an IC50 of 3.34 nM and a pIC50 of 8.48[1].

Product Specifications

UNSPSC

12352005

Target

Cathepsin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/tsc25.html

Solubility

10 mM in DMSO

Smiles

NC(N/N=C(C1=CC=C(C(Cl)=C1)Cl)\CCN2CCOCC2)=S

Molecular Formula

C14H18Cl2N4OS

Molecular Weight

361.29

References & Citations

[1]Jasinski G, et al. Design, synthesis and biological evaluation of novel thiosemicarbazones as cruzipain inhibitors. Eur J Med Chem. 2023 Apr 7;254:115345.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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