TSC24
Product Specifications
UNSPSC Description
TSC24, a thiosemicarbazone, is a potent cruzipain (CZP) inhibitor with an IC50 of 2.86 nM, a pIC50 of 8.54 and a pKa of 8.6. TSC24 has the potential for parasitic diseases research[1].
Target Antigen
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tsc24.html
Solubility
10 mM in DMSO
Smiles
NC(N/N=C(C1=CC=C(C(Cl)=C1)Cl)\CCN2CCCCC2)=S
Molecular Weight
359.32
References & Citations
[1]Gabriel Jasinski, et al. Design, synthesis and biological evaluation of novel thiosemicarbazones as cruzipain inhibitors. Eur J Med Chem. 2023 Apr 7;254:115345.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149068/TSC24-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149068/
Clinical Information
No Development Reported
Curated Selection
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