Diaporthein B
Product Specifications
CAS Number
[577705-64-7]
UNSPSC Description
Diaporthein B is one of the most highly oxidized pimarane diterpenes. Diaporthein B exhibits activity against M. tuberculosis, with a MIC of 3.1 μg/mL. Diaporthein B reveals IC50s of 1.5-3 μM against HCT 116 and LoVo colon cancer cells[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/diaporthein-b.html
Solubility
10 mM in DMSO
Smiles
O[C@]12[C@]3(CCCC2(C)C)[C@@]4(C(C([C@]1(OC3)O)=O)=C[C@](C)(C[C@H]4O)C=C)O
Molecular Weight
364.43
References & Citations
[1]Ian Tingyung Hsu, et al. Fragment Coupling Approach to Diaporthein B. J Org Chem. 2023 Feb 17;88(4):2221-2244.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
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