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Diaporthein B

Product Specifications

CAS Number

[577705-64-7]

UNSPSC Description

Diaporthein B is one of the most highly oxidized pimarane diterpenes. Diaporthein B exhibits activity against M. tuberculosis, with a MIC of 3.1 μg/mL. Diaporthein B reveals IC50s of 1.5-3 μM against HCT 116 and LoVo colon cancer cells[1].

Target Antigen

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/diaporthein-b.html

Solubility

10 mM in DMSO

Smiles

O[C@]12[C@]3(CCCC2(C)C)[C@@]4(C(C([C@]1(OC3)O)=O)=C[C@](C)(C[C@H]4O)C=C)O

Molecular Weight

364.43

References & Citations

[1]Ian Tingyung Hsu, et al. Fragment Coupling Approach to Diaporthein B. J Org Chem. 2023 Feb 17;88(4):2221-2244.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

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