Antitumor agent-92

Antitumor agent-92, an Icaritin (HY-N0678) derivative, causes arrest at the G0/G1 phase in the cell cycle and induces cell apoptosis. Antitumor agent-92 has the potential for hepatocellular carcinoma (HCC) research[1].

Product Specifications

CAS Number

[2922842-01-9]

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antitumor-agent-92.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=C(C=C1)C2=C(C(C3=C(C=C(C(C/C=C(C)\C)=C3O2)OCCN4CCCC4)O)=O)O[C@H]5O[C@@H]([C@H]([C@@H]([C@@H]5O)O)O)C

Molecular Formula

C33H41NO10

Molecular Weight

611.68

References & Citations

[1]Jichong Li, et al. Synthesis and Structure-Activity Analysis of Icaritin Derivatives as Potential Tumor Growth Inhibitors of Hepatocellular Carcinoma Cells. J Nat Prod. 2023 Feb 24;86 (2) :290-306.