Viral polymerase-IN-1 (hydrochloride)
Product Specifications
UNSPSC Description
Viral polymerase-IN-1 hydrochloride, a Gemcitabine (HY-17026) derivative, potently inhibits influenza A and B viruses infection with IC90 values of 11.4-15.9 μM. Viral polymerase-IN-1 hydrochloride is active against SARS-CoV-2 infection. Viral polymerase-IN-1 hydrochloride suppresses influenza virus infection by affecting viral RNA replication/transcription in cells[1].
Target Antigen
Influenza Virus; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/viral-polymerase-in-1-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](O)C(F)(F)[C@H](N2C=CC(NC(C3=NC=C(N)C=C3)=O)=NC2=O)O1.Cl
Molecular Weight
419.77
References & Citations
[1]Hyeon-Min Cha, et al. Evaluation of Antiviral Activity of Gemcitabine Derivatives against Influenza Virus and Severe Acute Respiratory Syndrome Coronavirus 2. ACS Infect Dis. 2023 Apr 14;9(4):1033-1045.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149050/Viral-polymerase-IN-1-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149050/
Clinical Information
No Development Reported
CAS Number
2367587-02-6
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