Viral polymerase-IN-1 (hydrochloride)
Viral polymerase-IN-1 hydrochloride, a Gemcitabine (HY-17026) derivative, potently inhibits influenza A and B viruses infection with IC90 values of 11.4-15.9 μM. Viral polymerase-IN-1 hydrochloride is active against SARS-CoV-2 infection. Viral polymerase-IN-1 hydrochloride suppresses influenza virus infection by affecting viral RNA replication/transcription in cells[1].
Product Specifications
CAS Number
[2367587-02-6]
UNSPSC
12352005
Target
Influenza Virus; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/viral-polymerase-in-1-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](O)C(F)(F)[C@H](N2C=CC(NC(C3=NC=C(N)C=C3)=O)=NC2=O)O1.Cl
Molecular Formula
C15H16ClF2N5O5
Molecular Weight
419.77
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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