Antitumor agent-70
Product Specifications
UNSPSC Description
Antitumor agent-70 (compound 8b) has anti-tumor activity and can induce cell apoptosis. Antitumor agent-70 inhibits multiple myeloma with an IC50 value of 0.12 μM. Antitumor agent-70 is a potential multi-targeted kinase inhibitor especially for c-Kit[1].
Target Antigen
Apoptosis; c-Kit
Type
Reference compound
Related Pathways
Apoptosis;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-70.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CN=C1)N/N=C/C2=CC=C(C(NC3=CC=C(C)C=C3)=O)C=C2
Molecular Weight
358.39
References & Citations
[1]Xin-Yang Li, et al. Design, synthesis and biological evaluation of novel (E)-N-phenyl-4-(pyridine-acylhydrazone) benzamide derivatives as potential antitumor agents for the treatment of multiple myeloma (MM). Bioorg Chem. 2020 Oct;103:104189.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149019/Antitumor-agent-70-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149019/
Clinical Information
No Development Reported
CAS Number
9007-83-4
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