ATX inhibitor 22
Product Specifications
UNSPSC Description
ATX inhibitor 22 is a novel inhibitor of ATX (autotaxin) with IC50 of 218 nM but lost its inhibitory activity of LPAR1[1].
Target Antigen
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atx-inhibitor-22.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(N(C1CCOCC1)C2=C(C=C(C(C(NC3=CC(F)=C(C(F)=C3)Cl)=O)=C2)Cl)Cl)=O
Molecular Weight
513.77
References & Citations
[1]Souvik Banerjee, et al. Molecular modelling guided design, synthesis and QSAR analysis of new small molecule non-lipid autotaxin inhibitors. Bioorg Chem. 2020 Oct; 103: 104188.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149018/ATX-inhibitor-22-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149018/
Clinical Information
No Development Reported
CAS Number
2969213-59-8
Curated Selection
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